Hacker News

Show HN: Playing with genomics foundation models | Tutorial/Explainer article

Hacker News - Mon, 06/01/2026 - 9:42pm

Hi folks,

I got curious about how genomics foundation models work and wrote an article explaining how they are trained + can be used.

Feel free to use the following as learning resources if you wish to jump into ML for comp bio stuff, it may help:

- Code: https://github.com/dillondesilva/nt-promoter-region-classifi...

- Article/Tutorial: https://substack.com/@dillondesilva/note/p-199596906?utm_sou...

- Demo: https://nt-promoter-region-classification.vercel.app/

Comments URL: https://news.ycombinator.com/item?id=48364882

Points: 1

# Comments: 0

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More Time to Think

Hacker News - Mon, 06/01/2026 - 9:34pm
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Crystal Nights by Greg Egan

Hacker News - Mon, 06/01/2026 - 9:22pm
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Show HN: NUA an agent that tests for product correctness

Hacker News - Mon, 06/01/2026 - 9:15pm

We’ve been using background Claude loops a lot recently, and we would wake up to PRs that didn’t solve the problem we wanted, made on assumptions that were wrong. Furthermore, the tests that the agents wrote were usually tautological, and didn’t test for intent. We wanted an agent that took all the context a company has, and writes tests that check for product correctness as well.

For example, we work in reg tech, so bugs aren’t always technical. What we often see is things like insider trading alerts that should’ve fired that didn’t. We wanted an agent that turns laws and regulations into tests.

For now, users can upload PDF, MD, TXT, and DOCX files, but we’re planning integrations like Slack, Notion, Linear, and Zoom in the future.

We’re early on, so we would love to know what you all think!

Comments URL: https://news.ycombinator.com/item?id=48364701

Points: 5

# Comments: 2

Categories: Hacker News

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